thyroid gland disease

ICD-10 Codes

Related ICD-10:

Description

Thyroid Gland Disease: An Overview

The thyroid gland, a small butterfly-shaped gland located in the front of the neck, plays a crucial role in regulating various bodily functions such as metabolism, growth, and development. However, when this gland becomes diseased, it can lead to a range of health issues.

Types of Thyroid Gland Disease

There are two main types of thyroid gland disease: hyperthyroidism and hypothyroidism [3]. Hyperthyroidism occurs when the thyroid gland produces too much thyroid hormone, leading to symptoms such as weight loss, rapid heartbeat, and anxiety. On the other hand, hypothyroidism is characterized by a deficiency in thyroid hormone production, resulting in symptoms like fatigue, weight gain, and depression.

Causes of Thyroid Gland Disease

Thyroid gland disease can be caused by various factors, including:

  • Autoimmune diseases: Conditions such as Graves' disease and Hashimoto's thyroiditis, where the immune system attacks the thyroid gland [6].
  • Iodine deficiency: A lack of iodine in the diet can lead to thyroid problems [8].
  • Primary vs. secondary thyroid disease: Primary thyroid disease originates in the thyroid gland itself, while secondary thyroid disease is caused by a problem in the pituitary gland [5].

Common Thyroid Disorders

Some common thyroid disorders include:

  • Hashimoto's disease: An autoimmune disorder affecting the thyroid gland [7].
  • Graves' disease: Another autoimmune condition that causes hyperthyroidism.
  • Goiter: A condition characterized by an enlarged thyroid gland.

In summary, thyroid gland disease can manifest in various ways, including hyperthyroidism and hypothyroidism, and can be caused by factors such as autoimmune diseases, iodine deficiency, and primary vs. secondary thyroid disease.

Additional Characteristics

  • Graves' disease
  • Autoimmune diseases
  • Goiter
  • hypothyroidism
  • hyperthyroidism
  • Iodine deficiency
  • Primary vs. secondary thyroid disease
  • Hashimoto's disease

Signs and Symptoms

Thyroid Gland Disease: Common Signs and Symptoms

The thyroid gland plays a crucial role in regulating various bodily functions, including metabolism, energy levels, and overall health. When the thyroid gland is not functioning properly, it can lead to several signs and symptoms.

Common Symptoms of Thyroid Dysfunction

  • Fatigue and weight gain [1]
  • Insomnia, constipation, hair loss, fluid retention, and temperature fluctuations [2]
  • Changes in heart rate, energy level, skin and hair texture, bowel movements, and mood [3]
  • Goiter (visibly enlarged thyroid gland) or thyroid nodules
  • Hair loss, hand tremors, and a low-pitched and hoarse voice [4]

Other Possible Symptoms

  • A puffy-looking face
  • Thinned or partly missing eyebrows
  • A slow heart rate
  • Hearing loss
  • Anaemia

Types of Thyroid Disease

Thyroid disease can manifest in different ways, including:

  • Hypothyroidism: Underactive thyroid gland, leading to fatigue and weight gain [1]
  • Hyperthyroidism: Overactive thyroid gland, causing symptoms like insomnia and hair loss [2]
  • Graves' disease: An autoimmune disorder that causes an enlarged thyroid gland and various symptoms [6]

Important Note

It's essential to consult a healthcare professional if you're experiencing any of these symptoms or have concerns about your thyroid health.

References: [1] - Context result 1 [2] - Context result 2 [3] - Context result 3 [4] - Context result 4 [6] - Context result 7

Additional Symptoms

  • Hearing loss
  • Anaemia
  • Fatigue and weight gain
  • Insomnia, constipation, hair loss, fluid retention, and temperature fluctuations
  • Changes in heart rate, energy level, skin and hair texture, bowel movements, and mood
  • Goiter (visibly enlarged thyroid gland) or thyroid nodules
  • Hair loss, hand tremors, and a low-pitched and hoarse voice
  • A puffy-looking face
  • Thinned or partly missing eyebrows
  • A slow heart rate

Diagnostic Tests

Thyroid Gland Diagnostic Tests

The diagnosis of thyroid gland diseases involves various tests to evaluate its functioning and identify any abnormalities. Here are some common diagnostic tests used for thyroid gland diseases:

  • Blood Tests: Blood tests are the first line of investigation for thyroid gland diseases. They measure the levels of thyroid hormones, such as TSH (Thyroid Stimulating Hormone), T4 (Thyroxine), and T3 (Triiodothyronine) in the blood [1][2]. These tests can help diagnose hypothyroidism, hyperthyroidism, and other thyroid disorders.
  • Thyroid Antibodies Test: This test measures certain thyroid antibodies (markers in the blood) to help diagnose autoimmune thyroid disorders, such as Hashimoto's thyroiditis or Graves' disease [3].
  • Imaging Tests: Imaging tests, such as thyroid ultrasound, can visualize nodules, lumps, and enlargement of the gland. Nuclear scans/radioactive iodine uptake tests can also be used to evaluate thyroid function and diagnose certain conditions [4].
  • Thyroid Panel: A thyroid panel uses a blood sample to evaluate the functioning of the thyroid gland and can help diagnose and monitor the treatment of thyroid disorders [5].

Common Blood Tests for Thyroid Function

The following blood tests are commonly used to check thyroid function:

  • TSH (Thyroid Stimulating Hormone)
  • T4 (Thyroxine)
  • T3 (Triiodothyronine)
  • Thyroid Antibodies

These tests can help diagnose hypothyroidism, hyperthyroidism, and other thyroid disorders.

References

[1] Context 1: Doctors may order one or more blood tests to check your thyroid function.

Treatment

Treatment Options for Thyroid Gland Diseases

The treatment options for thyroid gland diseases depend on the type and severity of the condition. Here are some common drug treatments:

  • Hypothyroidism: The main treatment option is thyroid replacement medication, which involves taking synthetic thyroid hormones to add them back into your body. Levothyroxine (Levo-T, Synthroid, others) is a commonly prescribed medication for this condition [3][4].
  • Hyperthyroidism: Anti-thyroid medicine can be used to treat an overactive thyroid by preventing the gland from making too many hormones [8].

Common Medications

Some common medications used to treat thyroid gland diseases include:

  • Levothyroxine (Levo-T, Synthroid, others)
  • Liothyronine (Cytomel, Liothyronine)
  • Thyroid hormone

Treatment Goals

The goal of thyroid hormone treatment is to closely replicate normal thyroid functioning [5]. This involves taking medication regularly to maintain optimal levels of thyroid hormones in the body.

Prevalence of Medication Use

According to a study, approximately 14% of women and 7.9% of all individuals use sulfonylureas, while 72% of men and 3.6% of all individuals use bisphosphonates [9].

Note: The information provided is based on the search results and may not be comprehensive or up-to-date. It's always best to consult a healthcare professional for personalized advice.

References:

[1] Context result 1 [2] Context result 2 [3] Context result 3 [4] Context result 4 [5] Context result 5 [6] Context result 6 [7] Context result 7 [8] Context result 8 [9] Context result 9

Recommended Medications

  • Sulfonylureas
  • Bisphosphonates
  • Levothyroxine (Levo-T, Synthroid, others)
  • Liothyronine (Cytomel, Liothyronine)
  • Anti-thyroid medicine
  • thyroid hormone

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

The differential diagnosis of thyroid gland diseases involves identifying and ruling out various conditions that can cause similar symptoms or physical findings. Here are some key points to consider:

  • Thyroid Goiter: A goiter is an enlargement of the thyroid gland, which can be caused by a variety of factors, including iodine deficiency, thyroiditis, or tumors [3]. The differential diagnosis for thyroid goiter includes conditions such as Hashimoto's thyroiditis, Graves' disease, and thyroid cancer [4].
  • Hyperthyroidism: Hyperthyroidism is characterized by an overproduction of thyroid hormones, which can be caused by conditions such as Graves' disease, toxic nodular goiter, or thyroiditis [7]. The differential diagnosis for hyperthyroidism includes conditions such as factitious hyperthyroidism (thyrotoxicosis factitia) and painless thyroiditis [11].
  • Hypothyroidism: Hypothyroidism is characterized by an underproduction of thyroid hormones, which can be caused by conditions such as Hashimoto's thyroiditis, thyroidectomy, or pituitary gland dysfunction [13]. The differential diagnosis for hypothyroidism includes conditions such as primary and secondary (central) hypothyroidism.
  • Thyroid Nodules: Thyroid nodules are discrete lesions within the thyroid gland, which can be caused by a variety of factors, including benign growths or cancer [5]. The differential diagnosis for thyroid nodules includes conditions such as follicular adenoma, thyroid cyst, and other thyroid malignancies.
  • Thyroid Cancer: Thyroid cancer is a type of cancer that affects the thyroid gland, which can be caused by genetic mutations or radiation exposure [15]. The differential diagnosis for thyroid cancer includes conditions such as goiter, thyroiditis, and other thyroid disorders.

In terms of specific diagnoses, some key points to consider include:

  • Graves' Disease: Graves' disease is an autoimmune disorder that causes hyperthyroidism, which can be diagnosed based on physical findings such as a diffusely enlarged thyroid gland [7].
  • Hashimoto's Thyroiditis: Hashimoto's thyroiditis is an autoimmune disorder that causes hypothyroidism, which can be diagnosed based on physical findings such as a goiter and laboratory tests showing low levels of thyroid hormones [3].
  • Thyroiditis: Thyroiditis is inflammation of the thyroid gland, which can cause symptoms such as pain and swelling in the neck [11].

Overall, the differential diagnosis of thyroid gland diseases requires a thorough evaluation of physical findings, laboratory tests, and patient history to rule out various conditions that can cause similar symptoms or physical findings.

Additional Information

oboInOwl#hasOBONamespace
disease_ontology
oboInOwl#id
DOID:50
core#notation
DOID:50
oboInOwl#hasDbXref
UMLS_CUI:C0040128
IAO_0000115
An endocrine system disease that is located_in the thyroid.
rdf-schema#label
thyroid gland disease
rdf-schema#subClassOf
http://purl.obolibrary.org/obo/DOID_8433
oboInOwl#inSubset
http://purl.obolibrary.org/obo/doid#NCIthesaurus
relatedICD
http://example.org/icd10/E07.9
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#equivalentClass
t436870
rdf-schema#domain
https://w3id.org/def/predibionto#has_symptom_9164
owl#annotatedSource
t436949

Medical Disclaimer: The information provided on this website is for general informational and educational purposes only.

It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.