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Leucovorin

CHEBI:CHEBI_15640

Definition

A formyltetrahydrofolic acid in which the formyl group is located at position 5.

Chemical Information

Molecular Formula
C20H23N7O7
Molecular Mass
473.43930
Charge
0
SMILES
[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12
InChI
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1
InChIKey
VVIAGPKUTFNRDU-ABLWVSNPSA-N

Alternative Names

  • (5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
  • 10-Formyl-7,8-dihydrofolic acid
  • 5-Formyl-5,6,7,8-tetrahydrofolic acid
  • 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
  • 5-Formyltetrahydrofolate
  • Acide folinique
  • folinate
  • Folinic acid
  • L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
  • Leucovorin
  • Leucovorinum
  • N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
  • N-[4-({[2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
  • N5-Formyl-5,6,7,8-tetrahydrofolic acid
  • N5-Formyltetrahydrofolic acid

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6313
oboInOwl#hasDbXref
Wikipedia:Folinic_acid
core#notation
CHEBI:15640

Additional References

Wikipedia:Folinic_acid

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
6313
oboInOwl#hasDbXref
Wikipedia:Folinic_acid
oboInOwl#hasAlternativeId
CHEBI:2057
oboInOwl#id
CHEBI:15640
core#notation
CHEBI:15640
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76971
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_65340
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_6703
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_105728
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_65340
owl#annotatedSource
t116126
owl#someValuesFrom
t3038425