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cabotegravir

CHEBI:CHEBI_172944

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (3S,11aR)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1.

Chemical Information

Molecular Formula
C19H17F2N3O5
Molecular Mass
405.358
Charge
0
SMILES
[H][C@@]12CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(O)=C3C(=O)N1[C@@H](C)CO2
InChI
InChI=1S/C19H17F2N3O5/c1-9-8-29-14-7-23-6-12(16(25)17(26)15(23)19(28)24(9)14)18(27)22-5-10-2-3-11(20)4-13(10)21/h2-4,6,9,14,26H,5,7-8H2,1H3,(H,22,27)/t9-,14+/m0/s1
InChIKey
WCWSTNLSLKSJPK-LKFCYVNXSA-N

Alternative Names

  • (3S,11aR)-N-(2,4-difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
  • CAB
  • cabotegravir
  • cabotegravirum
  • GSK 1265744
  • GSK 744
  • GSK-1265744
  • GSK-1265744A
  • GSK1265744
  • GSK1265744A
  • GSK744
  • GSK744 LA
  • GSK744 LAP
  • S-265744
  • S/GSK1265744

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2475077
oboInOwl#hasDbXref
Wikipedia:Cabotegravir
core#notation
CHEBI:172944

Additional References

Wikipedia:Cabotegravir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2475077
oboInOwl#hasDbXref
Wikipedia:Cabotegravir
oboInOwl#id
CHEBI:172944
core#notation
CHEBI:172944
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_67268
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_172947
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect8720
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_172947
owl#annotatedSource
t134283
owl#someValuesFrom
t3838815