Amiodarone
CHEBI:CHEBI_2663
Definition
A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Chemical Information
- Molecular Formula
- C25H29I2NO3
- Molecular Mass
- 645.31160
- Charge
- 0
- SMILES
- CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1
- InChI
- InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3
- InChIKey
- IYIKLHRQXLHMJQ-UHFFFAOYSA-N
Alternative Names
- (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
- 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
- 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
- 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
- amiodarona
- Amiodarone
- amiodaronum
Drug Classification
-
tertiary amino compoundView Class →
CHEBI:50996
-
1-benzofuransView Class →
CHEBI:38830
-
aromatic ketoneView Class →
CHEBI:76224
-
organoiodine compoundView Class →
CHEBI:37142
-
t154625
-
t154672
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:2663
- DRON_00010000
- 703
- oboInOwl#hasDbXref
- Wikipedia:Amiodarone
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- package_description
- 10 kg in 1 DRUM (14335-270-01)
- package_ndc
- 42419-017-02
- rxcui
- 1663248
- active_ingredient_strength
- 900 mg/18mL
- active_ingredient_name
- AMIODARONE
- unii
- 976728SY6Z
- spl_set_id
- 337c5695-e3f8-41c6-a088-a492d5c60215
- manufacturer_name
- HF Acquisition Co LLC, DBA HealthFirst
- upc
- 0055154818506
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- INJECTION, SOLUTION
- marketing_start_date
- 19961016
- labeler_name
- Zhejiang Poly Pharm. Co., Ltd.
- application_number
- ANDA077161
- product_ndc
- 72888-060
- listing_expiration_date
- 20241231
- route
- INTRAVENOUS
- spl_id
- d2c4aab0-2e5d-84b7-e053-2a95a90aef8b
- core#notation
- CHEBI:2663
- pharm_class
- Cytochrome P450 2C9 Inhibitors [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 703
- oboInOwl#hasDbXref
- Wikipedia:Amiodarone
- oboInOwl#id
- CHEBI:2663
- generic_name
- Amiodarone HCl
- brand_name
- Amiodarone hydrochloride
- brand_name_base
- Amiodarone hydrochloride
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35554
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00723854
- package_marketing_start_date
- 16-OCT-96
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0070535
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect11835
- owl#annotatedSource
- t155631
- owl#someValuesFrom
- t3000375