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desloratadine

CHEBI:CHEBI_291342

Definition

Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.

Chemical Information

Molecular Formula
C19H19ClN2
Molecular Mass
310.82100
Charge
0
SMILES
Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1
InChI
InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChIKey
JAUOIFJMECXRGI-UHFFFAOYSA-N

Alternative Names

  • 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
  • descarboethoxyloratadine
  • desloratadine
  • DESLORATADINE

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
275635
oboInOwl#hasDbXref
Wikipedia:Desloratadine
core#notation
CHEBI:291342

Additional References

Wikipedia:Desloratadine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
DRON_00010000
275635
oboInOwl#hasDbXref
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oboInOwl#id
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CHEBI:291342
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
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http://purl.obolibrary.org/obo/DOID_8892
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https://w3id.org/def/predibionto#has_side_effect14957
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_6538
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t169729
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t3004703