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Benztropine

CHEBI:CHEBI_3048

Definition

Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.

Chemical Information

Molecular Formula
C21H25NO
Molecular Mass
307.42930
Charge
0
SMILES
[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1
InChI
InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+
InChIKey
GIJXKZJWITVLHI-PMOLBWCYSA-N

Alternative Names

  • (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
  • 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane
  • 3alpha-(diphenylmethoxy)tropane
  • 3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
  • 3endo-benzhydryloxytropane
  • benzatropina
  • benzatropine
  • Benzatropine
  • benzatropinum
  • benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether
  • Benztropine
  • tropine benzohydryl ether

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1424
oboInOwl#hasDbXref
Wikipedia:Benzatropine
core#notation
CHEBI:3048

Additional References

Wikipedia:Benzatropine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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DRON_00010000
1424
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CHEBI:3048
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CHEBI:661238
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50370
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