Discuss This Drug

crotamiton

CHEBI:CHEBI_31439

Definition

An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.

Chemical Information

Molecular Formula
C13H17NO
Molecular Mass
203.28020
Charge
0
SMILES
CCN(C(=O)C=CC)c1ccccc1C
InChI
InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3
InChIKey
DNTGGZPQPQTDQF-UHFFFAOYSA-N

Alternative Names

  • crotalgin
  • crotamiton
  • crotamitone
  • crotamitonum
  • crotonyl-N-ethyl-o-toluidine
  • N-ethyl-N-(2-methylphenyl)but-2-enamide
  • N-ethyl-o-crotonotoluidide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
21766
oboInOwl#hasDbXref
Patent:GB615137
core#notation
CHEBI:31439

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
21766
oboInOwl#hasDbXref
Patent:GB615137
oboInOwl#id
CHEBI:31439
core#notation
CHEBI:31439
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_73333
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_8295
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110885
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect16755
owl#annotatedSource
t180231
owl#someValuesFrom
t587101