Droxidopa

CHEBI:CHEBI_31524

Definition

A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension

Chemical Information

Molecular Formula
C9H11NO5
Molecular Mass
213.18730
Charge
0
SMILES
N[C@@H]([C@H](O)c1ccc(O)c(O)c1)C(O)=O
InChI
InChI=1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1
InChIKey
QXWYKJLNLSIPIN-JGVFFNPUSA-N

Alternative Names

  • (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid
  • (2S,3R)-3,4-dihydroxy-phenylserine
  • (betaR)-beta,3-dihydroxy-L-tyrosine
  • Dops
  • droxidopa
  • droxidopum
  • Droxydopa
  • L-Dihydroxyphenylserine
  • L-DOPS
  • L-threo-dihydroxyphenylserine
  • L-Threodops
  • Northera
  • SM 5688
  • threo-Dopaserine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1489913
oboInOwl#hasDbXref
Wikipedia:Droxidopa
core#notation
CHEBI:31524

Additional References

Wikipedia:Droxidopa

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1489913
oboInOwl#hasDbXref
Wikipedia:Droxidopa
oboInOwl#id
CHEBI:31524
core#notation
CHEBI:31524
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0090145
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_105487
owl#annotatedSource
t180318
owl#someValuesFrom
t2990256