Discuss This Drug

febuxostat

CHEBI:CHEBI_31596

Definition

A 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout.

Chemical Information

Molecular Formula
C16H16N2O3S
Molecular Mass
316.380
Charge
0
SMILES
C1(=CC(=C(C=C1)OCC(C)C)C#N)C2=NC(=C(S2)C(=O)O)C
InChI
InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
InChIKey
BQSJTQLCZDPROO-UHFFFAOYSA-N

Alternative Names

  • 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
  • 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
  • Adenuric
  • Donifoxate
  • Febuday
  • Feburic
  • febuxostat
  • febuxostatum
  • Goturic
  • Goutex
  • TEI 6720
  • TEI-6720
  • TMX 67
  • TMX-67
  • Uloric
  • Zurig

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
73689
oboInOwl#hasDbXref
Wikipedia:Febuxostat
core#notation
CHEBI:31596

Additional References

Wikipedia:Febuxostat

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35634
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http://www.w3.org/2002/07/owl#Class
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