febuxostat
CHEBI:CHEBI_31596
Definition
A 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout.
Chemical Information
- Molecular Formula
- C16H16N2O3S
- Molecular Mass
- 316.380
- Charge
- 0
- SMILES
- C1(=CC(=C(C=C1)OCC(C)C)C#N)C2=NC(=C(S2)C(=O)O)C
- InChI
- InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
- InChIKey
- BQSJTQLCZDPROO-UHFFFAOYSA-N
Alternative Names
- 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
- 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
- Adenuric
- Donifoxate
- Febuday
- Feburic
- febuxostat
- febuxostatum
- Goturic
- Goutex
- TEI 6720
- TEI-6720
- TMX 67
- TMX-67
- Uloric
- Zurig
Treatment Applications
-
xanthinuriaView Disease →
DOID:0060236
Drug Classification
-
nitrileView Class →
CHEBI:18379
-
aromatic etherView Class →
CHEBI:35618
-
1,3-thiazolemonocarboxylic acidView Class →
CHEBI:48652
-
t180241
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:31596
- DRON_00010000
- 73689
- oboInOwl#hasDbXref
- Wikipedia:Febuxostat
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- package_description
- 60 kg in 1 DRUM (50379-0003-1)
- package_ndc
- 76397-005-02
- rxcui
- 834243
- package_marketing_start_date
- 29-JUN-15
- manufacturer_name
- DR REDDY'S LABORATORIES LIMITED
- unii
- 101V0R1N2E
- spl_set_id
- b2aeb900-d792-48b2-b678-94f82d68be32
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- FILM
- marketing_start_date
- 20160305
- labeler_name
- DR REDDY'S LABORATORIES LIMITED
- application_number
- ANDA205374
- product_ndc
- 59651-113
- listing_expiration_date
- 20241231
- route
- ORAL
- spl_id
- 0c897f74-3271-5403-e063-6294a90ad46c
- core#notation
- CHEBI:31596
- active_ingredient_strength
- 2 kg/2kg
- nui
- N0000000206
- pharm_class_epc
- Xanthine Oxidase Inhibitor [EPC]
- pharm_class
- Xanthine Oxidase Inhibitors [MoA]
- pharm_class_moa
- Xanthine Oxidase Inhibitors [MoA]
- active_ingredient_name
- FEBUXOSTAT
- upc
- 0372578136062
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 73689
- oboInOwl#hasDbXref
- Wikipedia:Febuxostat
- oboInOwl#id
- CHEBI:31596
- oboInOwl#hasAlternativeId
- CHEBI:45943
- generic_name
- Febuxostat tablets 40 mg
- brand_name
- ULORIC
- brand_name_base
- ULORIC
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35634
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0060350
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_101262
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect17000
- owl#annotatedSource
- t180298
- owl#someValuesFrom
- t999523