Fluorometholone

CHEBI:CHEBI_31625

Definition

A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Chemical Information

Molecular Formula
C22H29FO4
Molecular Mass
376.46170
Charge
0
SMILES
C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]2(C)C=CC(=O)C=C12
InChI
InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
InChIKey
FAOZLTXFLGPHNG-KNAQIMQKSA-N

Alternative Names

  • (6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
  • 9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
  • 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
  • Fluor-op
  • Fluorometholon
  • fluorometholone
  • fluorometholonum
  • fluorometolona
  • NSC 33001
  • Oxylone

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
4491
oboInOwl#hasDbXref
Wikipedia:Fluorometholone
core#notation
CHEBI:31625

Additional References

Wikipedia:Fluorometholone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
4491
oboInOwl#hasDbXref
Wikipedia:Fluorometholone
oboInOwl#id
CHEBI:31625
core#notation
CHEBI:31625
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35472
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_34073
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0110709
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110722
owl#annotatedSource
t180259
owl#someValuesFrom
t624776