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Proglumide

CHEBI:CHEBI_32058

Definition

A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.

Chemical Information

Molecular Formula
C18H26N2O4
Molecular Mass
334.41000
Charge
0
SMILES
CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1
InChI
InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)
InChIKey
DGMKFQYCZXERLX-UHFFFAOYSA-N

Alternative Names

  • (+-)-4-benzamido-N,N-dipropylglutaramic acid
  • (+-)-proglumide
  • (RS)-proglumide
  • DL-proglumide
  • proglumida
  • proglumide
  • proglumidum
  • rac-N(2)-benzoyl-N,N-dipropyl-alpha-glutamine
  • racemic proglumide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
8730
oboInOwl#hasDbXref
Wikipedia:Proglumide
core#notation
CHEBI:32058

Additional References

Wikipedia:Proglumide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
DRON_00010000
8730
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CHEBI:32058
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_73296
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BFO_0000051
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http://purl.obolibrary.org/obo/CHEBI_76263
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t897209