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Carbidopa

CHEBI:CHEBI_3395

Definition

The hydrate of 3-(3,4-dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.

Chemical Information

Molecular Formula
C10H16N2O5
Molecular Mass
244.24440
Charge
0
SMILES
O.C[C@@](Cc1ccc(O)c(O)c1)(NN)C(O)=O
InChI
InChI=1S/C10H14N2O4.H2O/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4,12-14H,5,11H2,1H3,(H,15,16);1H2/t10-;/m0./s1
InChIKey
QTAOMKOIBXZKND-PPHPATTJSA-N

Alternative Names

  • (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate
  • (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate
  • (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid monohydrate
  • (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid--water (1/1)
  • (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate
  • (S)-(-)-carbidopa hydrate
  • (S)-carbidopa hydrate
  • carbidopa
  • carbidopa hydrate
  • carbidopa monohydrate
  • carbidopum monohydricum
  • L-alpha-(3,4-dihydroxybenzyl)-alpha-hydrazinopropionic acid monohydrate

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Patent:US3462536
DRON_00010000
2019
core#notation
CHEBI:3395

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Patent:US3462536
DRON_00010000
2019
oboInOwl#hasAlternativeId
CHEBI:212626
oboInOwl#id
CHEBI:3395
core#notation
CHEBI:3395
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48560
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_39585
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0060963
owl#annotatedSource
t193750
owl#someValuesFrom
t2995969