Discuss This Drug

cidofovir anhydrous

CHEBI:CHEBI_3696

Definition

Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

Chemical Information

Molecular Formula
C8H14N3O6P
Molecular Mass
279.18700
Charge
0
SMILES
Nc1ccn(C[C@@H](CO)OCP(O)(O)=O)c(=O)n1
InChI
InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1
InChIKey
VWFCHDSQECPREK-LURJTMIESA-N

Alternative Names

  • cidofovir
  • ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
  • (S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid
  • (S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine
  • (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
  • (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine
  • (S)-HPMPC
  • [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid
  • 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
  • 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
  • CDV
  • Cidofovir
  • Cidofovir anhydrous

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Cidofovir
core#notation
CHEBI:3696

Additional References

Wikipedia:Cidofovir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cidofovir
oboInOwl#hasAlternativeId
CHEBI:666483
oboInOwl#id
CHEBI:3696
core#notation
CHEBI:3696
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_47868
oboInOwl#inSubset
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chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_530615
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http://www.w3.org/2002/07/owl#Class
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chebi#is_conjugate_base_of
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