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Clarithromycin

CHEBI:CHEBI_3732

Definition

The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.

Chemical Information

Molecular Formula
C38H69NO13
Molecular Mass
747.95340
Charge
0
SMILES
[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C)OC
InChI
InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChIKey
AGOYDEPGAOXOCK-KCBOHYOISA-N

Alternative Names

  • 6-O-methylerythromycin
  • 6-O-methylerythromycin A
  • CLA
  • clarithromycin
  • Clarithromycin
  • CLARITHROMYCIN
  • clarithromycina
  • clarithromycine
  • clarithromycinum
  • O(6)-methylerythromycin

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
21212
oboInOwl#hasDbXref
Reaxys:3581974
core#notation
CHEBI:3732

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
21212
oboInOwl#hasDbXref
Reaxys:3581974
oboInOwl#id
CHEBI:3732
core#notation
CHEBI:3732
oboInOwl#hasAlternativeId
CHEBI:670147
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48001
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4131
Antibiotic_Name
http://purl.obolibrary.org/obo/DOID_0040083
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113496
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect22453
owl#annotatedSource
t207688
owl#someValuesFrom
t2999747