Atazanavir

CHEBI:CHEBI_37924

Definition

A heavily substituted carbohydrazide that is an antiretroviral drug of the protease inhibitor (PI) class used to treat infection of human immunodeficiency virus (HIV).

Chemical Information

Molecular Formula: C38H52N6O7
Molecular Mass: 704.85550
Charge: 0
SMILES: COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(cc1)-c1ccccn1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C
InChI: InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
InChIKey: AXRYRYVKAWYZBR-GASGPIRDSA-N

Alternative Names

atazanavir
atazanavirum
ATZ
dimethyl (3S,8S,9S,12S)-9-benzyl-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-6-[4-(2-pyridyl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate

Treatment Applications

obsolete AIDS-related pelvic inflammatory disease
DOID:1261

View Disease →
obsolete HIV wasting syndrome
DOID:1313

View Disease →
obsolete AIDS-related Pneumocystis jirovecii pneumonia
DOID:13734

View Disease →
obsolete AIDS-related idiopathic thrombocytopenic purpura
DOID:4799

View Disease →

Drug Classification

carbohydrazide
CHEBI:35363

View Class →
t206900
t207358

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref: Wikipedia:Atazanavir
DRON_00010000: 343047
core#notation: CHEBI:37924

Additional References

Wikipedia:Atazanavir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Wikipedia:Atazanavir
DRON_00010000: 343047
oboInOwl#id: CHEBI:37924
core#notation: CHEBI:37924
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_35660
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
rdf-schema#range: https://w3id.org/def/predibionto#has_drug_111129
owl#annotatedSource: t207594
owl#someValuesFrom: t3000922