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Cyproheptadine

CHEBI:CHEBI_4046

Definition

The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Chemical Information

Molecular Formula
C21H21N
Molecular Mass
287.39810
Charge
0
SMILES
CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
InChI
InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
InChIKey
JJCFRYNCJDLXIK-UHFFFAOYSA-N

Alternative Names

  • 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
  • 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
  • 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
  • 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
  • 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
  • 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
  • 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine
  • 5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
  • ciproheptadina
  • cyproheptadine
  • cyproheptadine
  • Cyproheptadine
  • CYPROHEPTADINE
  • cyproheptadinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3013
oboInOwl#hasDbXref
Wikipedia:Cyproheptadine
core#notation
CHEBI:4046

Additional References

Wikipedia:Cyproheptadine

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Additional Attributes

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DRON_00010000
3013
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CHEBI:4046
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CHEBI:4046
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