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Dexamethasone

CHEBI:CHEBI_41879

Definition

A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.

Chemical Information

Molecular Formula
C22H29FO5
Molecular Mass
392.467
Charge
0
SMILES
C1=CC(C=C2[C@]1([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@]([C@@H](C4)C)(C(CO)=O)O)C)[H])[H])F)C)=O
InChI
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChIKey
UREBDLICKHMUKA-CXSFZGCWSA-N

Alternative Names

  • (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
  • 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol
  • 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • 9alpha-fluoro-16alpha-methylprednisolone
  • Aeroseb-Dex
  • Auxiron
  • Azium
  • Calonat
  • Corson
  • Cortisumman
  • Decacort
  • Decadron
  • Decaject
  • Decalix
  • Decameth
  • Dexacortal
  • Dexacortin
  • dexametasona
  • dexamethasone
  • dexamethasone
  • Dexamethasone
  • dexamethasonum
  • Dexason
  • Dexasone
  • DexPak
  • Diodex
  • fluormethylprednisolone
  • Hexadrol
  • Maxidex
  • Millicorten
  • Oradexon
  • Ozurdex
  • Solurex
  • Zema-Pak

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:41879
DRON_00010000
3264
oboInOwl#hasDbXref
Wikipedia:Dexamethasone

Additional References

Wikipedia:Dexamethasone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:41879
has_treatment
http://purl.obolibrary.org/obo/DOID_11389
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3264
oboInOwl#hasDbXref
Wikipedia:Dexamethasone
oboInOwl#hasAlternativeId
CHEBI:4461
oboInOwl#id
CHEBI:41879
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37962
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_8386
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000060
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23755
owl#annotatedSource
t218034
owl#someValuesFrom
t3364120