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Dexamethasone

CHEBI:CHEBI_41879

Definition

A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.

Chemical Information

Molecular Formula
C22H29FO5
Molecular Mass
392.467
Charge
0
SMILES
C1=CC(C=C2[C@]1([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@]([C@@H](C4)C)(C(CO)=O)O)C)[H])[H])F)C)=O
InChI
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChIKey
UREBDLICKHMUKA-CXSFZGCWSA-N

Alternative Names

  • (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
  • 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol
  • 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • 9alpha-fluoro-16alpha-methylprednisolone
  • Aeroseb-Dex
  • Auxiron
  • Azium
  • Calonat
  • Corson
  • Cortisumman
  • Decacort
  • Decadron
  • Decaject
  • Decalix
  • Decameth
  • Dexacortal
  • Dexacortin
  • dexametasona
  • dexamethasone
  • dexamethasone
  • Dexamethasone
  • dexamethasonum
  • Dexason
  • Dexasone
  • DexPak
  • Diodex
  • fluormethylprednisolone
  • Hexadrol
  • Maxidex
  • Millicorten
  • Oradexon
  • Ozurdex
  • Solurex
  • Zema-Pak

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3264
oboInOwl#hasDbXref
Wikipedia:Dexamethasone
core#notation
CHEBI:41879

Additional References

Wikipedia:Dexamethasone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

dosage_form
IMPLANT
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA216284
product_ndc
72189-254
brand_name
Mardex 25 Kit
brand_name_base
Mardex 25 Kit
generic_name
Dexamethasone Sodium Phosphate, Lidocaine Hydrochloride, Povidine Iodine
package_ndc
68788-7142-5
listing_expiration_date
20241231
spl_id
05911ad3-b94f-407c-a78f-dd9017933a08
marketing_start_date
20191221
package_marketing_start_date
20180402
package_description
25 VIAL, MULTI-DOSE in 1 CARTON (70069-024-25) / 30 mL in 1 VIAL, MULTI-DOSE (70069-024-01)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3264
oboInOwl#hasDbXref
Wikipedia:Dexamethasone
oboInOwl#hasAlternativeId
CHEBI:4461
oboInOwl#id
CHEBI:41879
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37962
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_8386
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000060
manufacturer_name
Guangdong Quadrant Ecological Technology Co., Ltd.
labeler_name
Amneal Pharmaceuticals LLC
active_ingredient_strength
.75 mg/.75mg
active_ingredient_name
DEXAMETHASONE ISONICOTINATE
spl_set_id
3166db4f-66a5-496a-a194-3cc01b7347d3
route
INTRACANALICULAR
rxcui
2286261
unii
AI9376Y64P
core#notation
CHEBI:41879
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
brand_name_suffix
1.5 mg
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
nui
N0000175450
upc
0382804132218
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23755
owl#annotatedSource
t218034
owl#someValuesFrom
t3364120
has_treatment
http://purl.obolibrary.org/obo/DOID_11389