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Dacarbazine

CHEBI:CHEBI_4305

Definition

A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.

Chemical Information

Molecular Formula
C6H10N6O
Molecular Mass
182.183
Charge
0
SMILES
C=1NC(=C(N1)C(=O)N)N=NN(C)C
InChI
InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)
InChIKey
FDKXTQMXEQVLRF-UHFFFAOYSA-N

Alternative Names

  • 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide
  • 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
  • 4-(dimethyltriazeno)imidazole-5-carboxamide
  • 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide
  • 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
  • 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
  • 5-(3,3-dimethyltriazeno)imidazole-4-carboxamide
  • 5-(dimethyltriazeno)imidazole-4-carboxamide
  • dacarbazina
  • dacarbazine
  • dacarbazinum
  • deticene
  • Di-me-triazenoimidazolecarboxamide
  • DIC
  • DTIC
  • Dtic-Dome (TN)
  • HSDB 3219
  • ICDMT
  • Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
  • NCI-C04717
  • NSC 45388
  • NSC-45388

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3098
oboInOwl#hasDbXref
Wikipedia:Dacarbazine
core#notation
CHEBI:4305

Additional References

Wikipedia:Dacarbazine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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DRON_00010000
3098
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CHEBI:4305
core#notation
CHEBI:4305
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_22333
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http://purl.obolibrary.org/obo/DOID_8567
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t2991577