Dextromethorphan
CHEBI:CHEBI_4470
Definition
A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.
Chemical Information
- Molecular Formula
- C18H25NO
- Molecular Mass
- 271.404
- Charge
- 0
- SMILES
- C=1C=2C[C@H]3[C@@]4([C@](C2C=C(C1)OC)(CCCC4)CCN3C)[H]
- InChI
- InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
- InChIKey
- MKXZASYAUGDDCJ-NJAFHUGGSA-N
Alternative Names
- (+)-3-methoxy-N-methylmorphinan
- (+)-dextromethorphan
- (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
- (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan
- 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
- 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
- Albutussin
- Antussan
- BA 2666
- BA-2666
- Balminil DM
- Benylin DM
- Calmylin
- d-Methorphan
- D-methorphan
- Delsym
- destrometerfano
- dextromethorfan
- dextromethorphan
- dextromethorphane
- dextromethorphanum
- dextrometorfano
- Dextromorphan
- DXM
- Medicon
- Romilar
- Tusilan
Drug Classification
-
t216849
-
t216860
-
t216962
-
t217170
-
t217447
-
t217554
-
t217611
-
t217614
-
t217866
-
t217930
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 3289
- oboInOwl#hasDbXref
- Wikipedia:Dextromethorphan
- core#notation
- CHEBI:4470
Additional References
Wikipedia:Dextromethorphan
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- brand_name
- Robafen DM Cough
- generic_name
- Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl
- product_ndc
- 53163-108
- brand_name_base
- Desgen
- dosage_form
- CRYSTAL
- product_type
- BULK INGREDIENT
- marketing_category
- EXPORT ONLY
- labeler_name
- Walgreen Company
- application_number
- ANDA088864
- route
- ORAL
- package_ndc
- 52083-660-16
- spl_id
- df1662fe-6e62-4093-a047-654e3b700ab3
- marketing_start_date
- 20181109
- listing_expiration_date
- 20241231
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 3289
- oboInOwl#hasDbXref
- Wikipedia:Dextromethorphan
- oboInOwl#id
- CHEBI:4470
- oboInOwl#hasAlternativeId
- CHEBI:92579
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50266
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_29133
- chebi#is_enantiomer_of
- http://purl.obolibrary.org/obo/CHEBI_146176
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00723856
- package_description
- 473 mL in 1 BOTTLE (45737-249-16)
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect6612
- owl#someValuesFrom
- t4001012
- owl#annotatedSource
- t221439
- package_marketing_start_date
- 20220223
- manufacturer_name
- AMZ789 LLC
- rxcui
- 2122356
- unii
- 6K9YKD48Y4
- spl_set_id
- 7c9660b7-cb00-449b-b65f-aa42d8ce1942
- nui
- N0000182147
- upc
- 0309047441204
- active_ingredient_strength
- 50 mg/2.5mL
- active_ingredient_name
- HEXYLRESORCINOL
- core#notation
- CHEBI:4470
- brand_name_suffix
- COUGH
- pharm_class
- Norepinephrine Uptake Inhibitors [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- pharm_class_epc
- Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]
- pharm_class_pe
- Increased Respiratory Secretions [PE]
- pharm_class_moa
- Uncompetitive NMDA Receptor Antagonists [MoA]