Trimethoprim

CHEBI:CHEBI_45924

Definition

An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Chemical Information

Molecular Formula: C14H18N4O3
Molecular Mass: 290.318
Charge: 0
SMILES: C=1(CC=2C(=NC(N)=NC2)N)C=C(C(OC)=C(C1)OC)OC
InChI: InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
InChIKey: IEDVJHCEMCRBQM-UHFFFAOYSA-N

Alternative Names

2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine
5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
Proloprim
Trimethoprim
TRIMETHOPRIM
Trimpex

Drug Classification

aminopyrimidine
CHEBI:38338

View Class →
methoxybenzenes
CHEBI:51683

View Class →
t220183
t220445
t220643
t221051
t221120
t221346

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref: Wikipedia:Trimethoprim
DRON_00010000: 10829
core#notation: CHEBI:45924

Additional References

Wikipedia:Trimethoprim

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Wikipedia:Trimethoprim
DRON_00010000: 10829
oboInOwl#hasAlternativeId: CHEBI:9731
prefixIRI: CHEBI:45924
oboInOwl#id: CHEBI:45924
core#notation: CHEBI:45924
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_50683
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
has_treatment: http://purl.obolibrary.org/obo/DOID_2381
owl#someValuesFrom: t712752
RO_0001022: http://purl.obolibrary.org/obo/DOID_0040029
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect386
owl#annotatedSource: t221499