Dobutamine

CHEBI:CHEBI_4670

Definition

A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.

Chemical Information

Molecular Formula
C18H23NO3
Molecular Mass
301.38010
Charge
0
SMILES
CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1
InChI
InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3
InChIKey
JRWZLRBJNMZMFE-UHFFFAOYSA-N

Alternative Names

  • (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
  • 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
  • 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
  • 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
  • DL-dobutamine
  • dobutamina
  • dobutamine
  • Dobutamine
  • DOBUTAMINE
  • dobutaminum
  • rac-dobutamine
  • racemic-dobutamine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3616
oboInOwl#hasDbXref
Wikipedia:Dobutamine
core#notation
CHEBI:4670

Additional References

Wikipedia:Dobutamine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
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DRON_00010000
3616
oboInOwl#hasDbXref
Wikipedia:Dobutamine
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CHEBI:554519
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CHEBI:4670
core#notation
CHEBI:4670
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35522
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22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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https://w3id.org/def/predibionto#has_drug_101653
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http://purl.obolibrary.org/obo/DOID_3827
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https://w3id.org/def/predibionto#has_side_effect24851
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