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esmolol

CHEBI:CHEBI_4856

Definition

A racemate comprising equimolar amounts of (R)- and (S)-esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. While the S enantiomer possesses all of the heart rate control, both enantiomers contribute to lowering blood pressure.

Chemical Information

Molecular Formula
C16H25NO4
Molecular Mass
295.375
Charge
0

Alternative Names

  • (+-)-esmolol
  • (+-)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate
  • 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester
  • esmolol
  • Esmolol
  • ESMOLOL
  • esmololum
  • Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate
  • methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate
  • rac-methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
49737
oboInOwl#hasDbXref
Wikipedia:Esmolol
core#notation
CHEBI:4856

Additional References

Wikipedia:Esmolol

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Additional Attributes

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chebi_ontology
DRON_00010000
49737
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http://purl.obolibrary.org/obo/DRON_00020323
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_60075
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