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Ethambutol

CHEBI:CHEBI_4877

Definition

An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.

Chemical Information

Molecular Formula
C10H24N2O2
Molecular Mass
204.30980
Charge
0
SMILES
CC[C@@H](CO)NCCN[C@@H](CC)CO
InChI
InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1
InChIKey
AEUTYOVWOVBAKS-UWVGGRQHSA-N

Alternative Names

  • (+)-2,2'-(ethylenediimino)di-1-butanol
  • (+)-ethambutol
  • (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine
  • (+)-S,S-ethambutol
  • (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol
  • (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol
  • (S,S)-ethambutol
  • EMB
  • etambutol
  • ethambutol
  • Ethambutol
  • ethambutolum
  • S,S-Ethambutol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Ethambutol
DRON_00010000
4110
core#notation
CHEBI:4877

Additional References

Wikipedia:Ethambutol

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Additional Attributes

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