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deferasirox

CHEBI:CHEBI_49005

Definition

A member of the class of triazoles, deferasirox is 1,2,4-triazole substituted by a 4-carboxyphenyl group at position 1 and by 2-hydroxyphenyl groups at positions 3 and 5. An orally active iron chelator, it is used to manage chronic iron overload in patients receiving long-term blood transfusions.

Chemical Information

Molecular Formula
C21H15N3O4
Molecular Mass
373.36162
Charge
0
SMILES
OC(=O)c1ccc(cc1)-n1nc(nc1-c1ccccc1O)-c1ccccc1O
InChI
InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,25-26H,(H,27,28)
InChIKey
BOFQWVMAQOTZIW-UHFFFAOYSA-N

Alternative Names

  • 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
  • deferasirox
  • deferasiroxum
  • Exjade
  • ICL 670
  • ICL 670A

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
614373
oboInOwl#hasDbXref
Reaxys:8442898
core#notation
CHEBI:49005

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
614373
oboInOwl#hasDbXref
Reaxys:8442898
oboInOwl#id
CHEBI:49005
core#notation
CHEBI:49005
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38157
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_855
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_2350
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26298
owl#annotatedSource
t231629
owl#someValuesFrom
t3161047