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mercaptopurine

CHEBI:CHEBI_50667

Definition

A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.

Chemical Information

Molecular Formula
C5H4N4S
Molecular Mass
152.17822
Charge
0
SMILES
S=c1[nH]cnc2nc[nH]c12
InChI
InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
InChIKey
GLVAUDGFNGKCSF-UHFFFAOYSA-N

Alternative Names

  • 6-MP
  • 6-Thiohypoxanthine
  • 1,7-dihydro-6H-purine-6-thione
  • 6 MP
  • 6-Mercaptopurine
  • 6-Thioxopurine
  • Mercaptopurina
  • mercaptopurine
  • mercaptopurine
  • Mercaptopurine
  • mercaptopurinum
  • Mercapurin
  • Puri-Nethol
  • Purinethol

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Reaxys:132916
DRON_00010000
103
core#notation
CHEBI:50667

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Reaxys:132916
DRON_00010000
103
oboInOwl#id
CHEBI:50667
core#notation
CHEBI:50667
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_tautomer_of
http://purl.obolibrary.org/obo/CHEBI_2208
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_11606
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113315
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect13558
owl#someValuesFrom
t3005030
owl#annotatedSource
t238770