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donepezil

CHEBI:CHEBI_53289

Definition

A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

Chemical Information

Molecular Formula
C24H29NO3
Molecular Mass
379.500
Charge
0
SMILES
C1(=C(C=C2C(=C1)CC(C2=O)(CC3CCN(CC3)CC4=CC=CC=C4)[H])OC)OC
InChI
InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
InChIKey
ADEBPBSSDYVVLD-UHFFFAOYSA-N

Alternative Names

  • donepezil
  • donepezilo
  • donepezilum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
135447
oboInOwl#hasDbXref
Wikipedia:Donepezil
core#notation
CHEBI:53289

Additional References

Wikipedia:Donepezil

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
DRON_00010000
135447
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CHEBI:53289
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38462
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BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_53292
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http://www.w3.org/2002/07/owl#Class
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t245760