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irbesartan

CHEBI:CHEBI_5959

Definition

A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

Chemical Information

Molecular Formula
C25H28N6O
Molecular Mass
428.52966
Charge
0
SMILES
CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI
InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)
InChIKey
YOSHYTLCDANDAN-UHFFFAOYSA-N

Alternative Names

  • 2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
  • 2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
  • Avapro
  • BMS 186295
  • irbesartan
  • Irbesartan

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
83818
oboInOwl#hasDbXref
Wikipedia:Irbesartan
core#notation
CHEBI:5959

Additional References

Wikipedia:Irbesartan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
83818
brand_name
Avalide
brand_name_base
Avalide
oboInOwl#hasDbXref
Wikipedia:Irbesartan
oboInOwl#id
CHEBI:5959
generic_name
irbesartan and hydrochlorothiazide
product_ndc
71205-063
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_61016
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00724207
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
POWDER
labeler_name
Zhuhai Rundu Pharmaceutical Co., Ltd.
application_number
ANDA201531
route
ORAL
package_ndc
43547-374-03
spl_id
199cc847-805e-4e1d-ae90-50cc59e7b3c0
package_marketing_start_date
15-FEB-09
package_description
90 TABLET in 1 BOTTLE, PLASTIC (29300-212-19)
active_ingredient_name
IRBESARTAN
active_ingredient_strength
50 kg/50kg
nui
N0000175561
upc
0300938238569
spl_set_id
029a90b6-0722-49be-8400-3ec29526aafd
core#notation
CHEBI:5959
pharm_class_epc
Angiotensin 2 Receptor Blocker [EPC]
pharm_class
Angiotensin 2 Receptor Blocker [EPC]
pharm_class_pe
Increased Diuresis [PE]
pharm_class_cs
Thiazides [CS]
pharm_class_moa
Angiotensin 2 Receptor Antagonists [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
823938
manufacturer_name
Hisun Pharmaceuticals USA Inc.
unii
J0E2756Z7N
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29594
owl#annotatedSource
t252640
owl#someValuesFrom
t952929
listing_expiration_date
20241231
marketing_start_date
20090215