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Isotretinoin

CHEBI:CHEBI_6067

Definition

A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.

Chemical Information

Molecular Formula
C20H28O2
Molecular Mass
300.43512
Charge
0
SMILES
CC(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C\C(O)=O
InChI
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChIKey
SHGAZHPCJJPHSC-XFYACQKRSA-N

Alternative Names

  • (2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
  • (7E,9E,11E,13Z)-retinoic acid
  • 13-cis-retinoic acid
  • 13-cis-Vitamin A acid
  • 13-RA
  • Accutane
  • Amnesteem
  • cis-RA
  • Claravis
  • isotretinoin
  • isotretinoina
  • isotretinoine
  • isotretinoino
  • isotretinoinum
  • Neovitamin A acid

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6064
oboInOwl#hasDbXref
Wikipedia:Isotretinoin
core#notation
CHEBI:6067

Additional References

Wikipedia:Isotretinoin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
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6064
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chebi#is_conjugate_base_of
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t256055