Discuss This Drug

Sotalol

CHEBI:CHEBI_63622

Definition

A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Chemical Information

Molecular Formula
C12H20N2O3S
Molecular Mass
272.36400
Charge
0
SMILES
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
InChI
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
InChIKey
ZBMZVLHSJCTVON-UHFFFAOYSA-N

Alternative Names

  • 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide
  • beta-cardone
  • N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide
  • sotalol
  • Sotalol
  • sotalolum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
9947
oboInOwl#hasDbXref
Wikipedia:Sotalol
core#notation
CHEBI:63622

Additional References

Wikipedia:Sotalol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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