Discuss This Drug

tolcapone

CHEBI:CHEBI_63630

Definition

Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase.

Chemical Information

Molecular Formula
C14H11NO5
Molecular Mass
273.24080
Charge
0
SMILES
Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O
InChI
InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
InChIKey
MIQPIUSUKVNLNT-UHFFFAOYSA-N

Alternative Names

  • (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
  • 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone
  • 3,4-Dihydroxy-4'-methyl-5-nitrobenzophenone
  • 3,4-dihydroxy-5-nitro-4'-methylbenzophenone
  • 4'-methyl-3,4-dihydroxy-5-nitrobenzophenone
  • tolcapone

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
72937
core#notation
CHEBI:63630
oboInOwl#hasDbXref
Wikipedia:Tolcapone

Additional References

Wikipedia:Tolcapone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
72937
oboInOwl#id
CHEBI:63630
core#notation
CHEBI:63630
oboInOwl#hasAlternativeId
CHEBI:9617
oboInOwl#hasDbXref
Wikipedia:Tolcapone
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48406
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30727
owl#annotatedSource
t262945
owl#someValuesFrom
t719496