Discuss This Drug

topiramate

CHEBI:CHEBI_63631

Definition

A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.

Chemical Information

Molecular Formula
C12H21NO8S
Molecular Mass
339.36200
Charge
0
SMILES
CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
InChI
InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1
InChIKey
KJADKKWYZYXHBB-XBWDGYHZSA-N

Alternative Names

  • 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
  • 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
  • McN-4853
  • RWJ-17021
  • tipiramate
  • tipiramato
  • Topamax
  • topiramate
  • Topiramate
  • topiramato
  • topiramatum
  • TPM

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
38404
oboInOwl#hasDbXref
Wikipedia:Topiramate
core#notation
CHEBI:63631

Additional References

Wikipedia:Topiramate

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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DRON_00010000
38404
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CHEBI:9633
RO_0000087
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BFO_0000053
http://purl.obolibrary.org/obo/DRON_00698710
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