Discuss This Drug

vismodegib

CHEBI:CHEBI_66903

Definition

A benzamide obtained by formal condensation between the carboxy group of 2-chloro-4-(methylsulfonyl)benzoic acid and the anilino group of 4-chloro-3-(pyridin-2-yl)aniline. Used for the treatment metastatic basal cell carcinoma.

Chemical Information

Molecular Formula
C19H14Cl2N2O3S
Molecular Mass
421.29700
Charge
0
SMILES
CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(c2)-c2ccccn2)c(Cl)c1
InChI
InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
InChIKey
BPQMGSKTAYIVFO-UHFFFAOYSA-N

Alternative Names

  • 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-(methylsulfonyl)benzamide
  • Erivedge
  • vismodegib
  • vismodegibum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1242987
oboInOwl#hasDbXref
Wikipedia:Vismodegib
core#notation
CHEBI:66903

Additional References

Wikipedia:Vismodegib

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1242987
oboInOwl#hasDbXref
Wikipedia:Vismodegib
oboInOwl#id
CHEBI:66903
core#notation
CHEBI:66903
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_66908
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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http://purl.obolibrary.org/obo/DOID_6609
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https://w3id.org/def/predibionto#has_drug_112746
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31534
owl#annotatedSource
t269884
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t1102112