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abiraterone

CHEBI:CHEBI_68642

Definition

A 3beta-sterol that is androsta-5,16-dien-3beta-ol substituted at position 17 by a 3-pyridyl group. Administered as the O-acetate, it is used for treatment of metastatic castrate-resistant prostate cancer.

Chemical Information

Molecular Formula
C24H31NO
Molecular Mass
349.50900
Charge
0
SMILES
[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=CC[C@@]21[H])c1cccnc1
InChI
InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1
InChIKey
GZOSMCIZMLWJML-VJLLXTKPSA-N

Alternative Names

  • (3beta)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol
  • 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
  • 17-(pyridin-3-yl)androsta-5,16-dien-3beta-ol
  • abiraterone

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Abiraterone
DRON_00010000
1100072
core#notation
CHEBI:68642

Additional References

Wikipedia:Abiraterone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Abiraterone
DRON_00010000
1100072
generic_name
ABIRATERONE
oboInOwl#id
CHEBI:68642
brand_name
YONSA
brand_name_base
YONSA
product_ndc
54893-0070
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68640
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35509
rxcui
2046585
active_ingredient_strength
1000 g/1000g
pharm_class
Cytochrome P450 2C8 Inhibitors [MoA]
manufacturer_name
Novugen Pharma (USA) LLC
active_ingredient_name
ABIRATERONE
unii
EM5OCB9YJ6
spl_set_id
f308b463-27e4-422a-95a2-ecbbf95eee20
upc
0382293001101
package_marketing_start_date
18-OCT-19
listing_expiration_date
20241231
marketing_start_date
20130731
spl_id
0cdca9ae-195e-0bd9-e063-6394a90a2765
labeler_name
CivicaScript, LLC
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
POWDER
application_number
ANDA215947
core#notation
CHEBI:68642
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
route
ORAL
package_ndc
54893-0070-1
package_description
50 kg in 1 DRUM (54893-0070-1)
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112952
has_treatment
http://purl.obolibrary.org/obo/DOID_3026
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32657
owl#annotatedSource
t276822
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t3992115