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ceftaroline

CHEBI:CHEBI_70729

Definition

A cephalosporin that is the active metabolite of the prodrug ceftaroline fosamil. Used for the treatment of adults with acute bacterial skin and skin structure infections.

Chemical Information

Molecular Formula
C22H20N8O5S4
Molecular Mass
604.70500
Charge
0
SMILES
[H][C@]12SCC(Sc3nc(cs3)-c3cc[n+](C)cc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC)\c1nsc(N)n1)C([O-])=O
InChI
InChI=1S/C22H20N8O5S4/c1-3-35-27-13(16-26-21(23)39-28-16)17(31)25-14-18(32)30-15(20(33)34)12(9-36-19(14)30)38-22-24-11(8-37-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H3-,23,25,26,28,31,33,34)/b27-13-/t14-,19-/m1/s1
InChIKey
RGFBRLNVZCCMSV-BIRGHMBHSA-N

Alternative Names

  • (6R,7R)-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetyl]amino}-3-{[4-(1-methylpyridinium-4-yl)-1,3-thiazol-2-yl]sulfanyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • PPI 0903M
  • T 91825
  • T-91825

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1040005
oboInOwl#hasDbXref
Reaxys:9532372
core#notation
CHEBI:70729

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1040005
oboInOwl#hasDbXref
Reaxys:9532372
oboInOwl#id
CHEBI:70729
core#notation
CHEBI:70729
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49103
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107099
has_treatment
http://purl.obolibrary.org/obo/DOID_12375
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_70718
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33151
owl#annotatedSource
t276761
owl#someValuesFrom
t666632