telavancin

CHEBI:CHEBI_71229

Definition

A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria.

Chemical Information

Molecular Formula: C80H106Cl2N11O27P
Molecular Mass: 1755.63500
Charge: 0
SMILES: CCCCCCCCCCNCCN[C@@]1(C)C[C@@H](O[C@@H](C)[C@H]1O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(cc3Cl)[C@@H](O)[C@@H](NC(=O)[C@@H](CC(C)C)NC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]4C(=O)N[C@@H]([C@H](O)c5ccc(Oc1cc3c2)c(Cl)c5)C(=O)N[C@H](C(O)=O)c1cc(O)c(CNCP(O)(O)=O)c(O)c1-c1cc4ccc1O
InChI: InChI=1S/C80H106Cl2N11O27P/c1-7-8-9-10-11-12-13-14-21-85-22-23-87-80(5)32-57(115-37(4)71(80)103)119-70-68(102)67(101)55(34-94)118-79(70)120-69-53-28-41-29-54(69)117-52-20-17-40(27-46(52)82)65(99)63-77(109)91-61(78(110)111)43-30-50(96)44(33-86-35-121(112,113)114)66(100)58(43)42-25-38(15-18-49(42)95)59(74(106)93-63)90-75(107)60(41)89-73(105)48(31-56(83)97)88-76(108)62(92-72(104)47(84-6)24-36(2)3)64(98)39-16-19-51(116-53)45(81)26-39/h15-20,25-30,36-37,47-48,55,57,59-65,67-68,70-71,79,84-87,94-96,98-103H,7-14,21-24,31-35H2,1-6H3,(H2,83,97)(H,88,108)(H,89,105)(H,90,107)(H,91,109)(H,92,104)(H,93,106)(H,110,111)(H2,112,113,114)/t37-,47+,48-,55+,57-,59+,60+,61-,62+,63-,64+,65+,67+,68-,70+,71+,79-,80-/m0/s1
InChIKey: ONUMZHGUFYIKPM-MXNFEBESSA-N

Alternative Names

N(3'')-[2-(decylamino)ethyl]-29-{[(phosphonomethyl)amino]methyl}vancomycin
telavancin
telavancina
telavancine
telavancinum

Treatment Applications

neomycin sulfate allergic contact dermatitis
DOID:0040067

View Disease →
junctional epidermolysis bullosa
DOID:3209

View Disease →
obsolete infectious ectromelia
DOID:3296

View Disease →

Drug Classification

glycopeptide
CHEBI:24396

View Class →
t279401
t279823

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref: Wikipedia:Telavancin
DRON_00010000: 473837
core#notation: CHEBI:71229

Additional References

Wikipedia:Telavancin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Wikipedia:Telavancin
DRON_00010000: 473837
oboInOwl#id: CHEBI:71229
core#notation: CHEBI:71229
chebi#has_functional_parent: http://purl.obolibrary.org/obo/CHEBI_28001
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
has_treatment: http://purl.obolibrary.org/obo/DOID_2176
rdf-schema#range: https://w3id.org/def/predibionto#has_drug_110246
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect33312
owl#annotatedSource: t280283
owl#someValuesFrom: t651875