Discuss This Drug

nabumetone

CHEBI:CHEBI_7443

Definition

A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

Chemical Information

Molecular Formula
C15H16O2
Molecular Mass
228.28630
Charge
0
SMILES
COc1ccc2cc(CCC(C)=O)ccc2c1
InChI
InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3
InChIKey
BLXXJMDCKKHMKV-UHFFFAOYSA-N

Alternative Names

  • 4-(6-Methoxy-2-naphthalenyl)-2-butanone
  • 4-(6-Methoxy-2-naphthyl)-2-butanone
  • nabumetona
  • nabumetone
  • nabumetonum
  • Relafen

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
31448
oboInOwl#hasDbXref
Wikipedia:Nabumetone
core#notation
CHEBI:7443

Additional References

Wikipedia:Nabumetone

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Additional Attributes

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chebi_ontology
DRON_00010000
31448
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CHEBI:7443
core#notation
CHEBI:7443
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50629
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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https://w3id.org/def/predibionto#has_side_effect33822
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t283720
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