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Naltrexone

CHEBI:CHEBI_7465

Definition

An organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A mu-opioid receptor antagonist, it is used to treat alcohol dependence.

Chemical Information

Molecular Formula
C20H23NO4
Molecular Mass
341.40096
Charge
0
SMILES
Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC1CC1
InChI
InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
InChIKey
DQCKKXVULJGBQN-XFWGSAIBSA-N

Alternative Names

  • 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
  • 17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one
  • 3,14-dihydroxy-17-(cyclopropylmethyl)-4,5alpha-epoxymorphinan-6-one
  • N-Cyclopropylmethyl-14-hydroxydihydromorphinone
  • N-Cyclopropylmethylnoroxymorphone
  • naltrexone
  • Naltrexone

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7243
oboInOwl#hasDbXref
Wikipedia:Naltrexone
core#notation
CHEBI:7465

Additional References

Wikipedia:Naltrexone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

has_treatment
http://purl.obolibrary.org/obo/DOID_13781
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7243
oboInOwl#hasDbXref
Wikipedia:Naltrexone
oboInOwl#id
CHEBI:7465
core#notation
CHEBI:7465
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_90755
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_134688
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000038
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6193
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_134688
owl#someValuesFrom
t3047044
owl#annotatedSource
t283710