Discuss This Drug

dabrafenib

CHEBI:CHEBI_75045

Definition

An organofluorine compound and antineoplastic agent, used as its mesylate salt in treatment of metastatic melanoma.

Chemical Information

Molecular Formula
C23H20F3N5O2S2
Molecular Mass
519.56200
Charge
0
SMILES
CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(s1)-c1ccnc(N)n1
InChI
InChI=1S/C23H20F3N5O2S2/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25/h4-11,31H,1-3H3,(H2,27,28,29)
InChIKey
BFSMGDJOXZAERB-UHFFFAOYSA-N

Alternative Names

  • dabrafenib
  • N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1424911
oboInOwl#hasDbXref
Wikipedia:Dabrafenib
core#notation
CHEBI:75045

Additional References

Wikipedia:Dabrafenib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1424911
oboInOwl#hasDbXref
Wikipedia:Dabrafenib
oboInOwl#id
CHEBI:75045
core#notation
CHEBI:75045
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_75047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113907
has_treatment
http://purl.obolibrary.org/obo/DOID_6089
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect34100
owl#annotatedSource
t287120
owl#someValuesFrom
t3951592