pioglitazone

CHEBI:CHEBI_8228

Definition

A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Chemical Information

Molecular Formula: C19H20N2O3S
Molecular Mass: 356.43978
Charge: 0
SMILES: CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
InChI: InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
InChIKey: HYAFETHFCAUJAY-UHFFFAOYSA-N

Alternative Names

(+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
pioglitazona
pioglitazone
Pioglitazone
pioglitazonum

Drug Classification

pyridines
CHEBI:26421

View Class →
aromatic ether
CHEBI:35618

View Class →
thiazolidinediones
CHEBI:50990

View Class →
t303467
t303558
t303590
t303770
t303816
t303906
t303941
t304001
t304071

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

core#notation: CHEBI:8228
oboInOwl#hasDbXref: Wikipedia:Pioglitazone
DRON_00010000: 33738

Additional References

Wikipedia:Pioglitazone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type: BULK INGREDIENT
marketing_category: BULK INGREDIENT
dosage_form: POWDER
product_ndc: 71335-9664
package_ndc: 63629-3299-1
active_ingredient_strength: 850 mg/1
active_ingredient_name: PIOGLITAZONE
nui: M0447306
upc: 0368071496437
spl_set_id: 164c444c-7c56-4482-9cbd-0e0f0ad30c44
package_description: 30 TABLET in 1 BOTTLE (42291-959-30)
listing_expiration_date: 20241231
labeler_name: Teva API India Limited
marketing_start_date: 20030303
application_number: NDA021925
spl_id: 1dd2c002-73ff-b183-e063-6294a90a5b65
package_marketing_start_date: 03-MAR-03
route: ORAL
core#notation: CHEBI:8228
pharm_class: Peroxisome Proliferator-activated Receptor gamma Agonists [MoA]
pharm_class_epc: Thiazolidinedione [EPC]
pharm_class_moa: Peroxisome Proliferator-activated Receptor gamma Agonists [MoA]
pharm_class_cs: Thiazolidinediones [CS]
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
rxcui: 731463
manufacturer_name: REMEDYREPACK INC.
unii: X4OV71U42S
has_treatment: http://purl.obolibrary.org/obo/DOID_11712
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect36064
owl#annotatedSource: t304093
owl#someValuesFrom: t3005090
oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Wikipedia:Pioglitazone
DRON_00010000: 33738
oboInOwl#id: CHEBI:8228
generic_name: Pioglitazone hydrochloride
brand_name: Duetact
brand_name_base: Duetact
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_83157
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR