Discuss This Drug

prednisolone

CHEBI:CHEBI_8378

Definition

A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Chemical Information

Molecular Formula
C21H28O5
Molecular Mass
360.44400
Charge
0
SMILES
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
InChI
InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChIKey
OIGNJSKKLXVSLS-VWUMJDOOSA-N

Alternative Names

  • (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
  • 1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione
  • 1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol
  • 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
  • 3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene
  • Delta(1)-dehydrocortisol
  • Delta(1)-dehydrohydrocortisone
  • Delta(1)-hydrocortisone
  • hydroretrocortine
  • metacortandralone
  • prednisolona
  • prednisolone
  • prednisolonum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:8378
DRON_00010000
8638
oboInOwl#hasDbXref
Wikipedia:Prednisolone

Additional References

Wikipedia:Prednisolone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_marketing_start_date
25-NOV-10
package_description
120 mL in 1 BOTTLE (68791-104-04)
route
OPHTHALMIC
package_ndc
46439-8761-4
spl_id
1dac5d28-4595-4fff-b729-0933c234f603
listing_expiration_date
20241231
marketing_start_date
20101125
labeler_name
Bausch & Lomb Incorporated
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SUSPENSION/ DROPS
application_number
ANDA040775
product_ndc
82298-106
rxcui
1376336
manufacturer_name
Seton Pharmaceuticals, LLC
unii
9PHQ9Y1OLM
spl_set_id
86652e2d-664a-4388-a611-c2a9aa4a4bc8
core#notation
CHEBI:8378
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
nui
N0000175450
active_ingredient_strength
20 mg/5mL
active_ingredient_name
PREDNISOLONE 21-PHOSPHATE
brand_name_suffix
ODT
upc
0301210759086
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8638
oboInOwl#hasDbXref
Wikipedia:Prednisolone
oboInOwl#id
CHEBI:8378
generic_name
Prednisolone Hemisuccinate
brand_name
PrednisoLONE
brand_name_base
PrednisoLONE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37962
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_53776
has_treatment
http://purl.obolibrary.org/obo/DOID_853
owl#someValuesFrom
t599845
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect18006
owl#annotatedSource
t307527