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Prednisone

CHEBI:CHEBI_8382

Definition

A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Chemical Information

Molecular Formula
C21H26O5
Molecular Mass
358.42810
Charge
0
SMILES
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
InChI
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChIKey
XOFYZVNMUHMLCC-ZPOLXVRWSA-N

Alternative Names

  • 1,2-Dehydrocortisone
  • 1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
  • 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
  • 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
  • Dehydrocortisone
  • prednison
  • prednisona
  • prednisone
  • prednisonum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Prednisone
DRON_00010000
8640
core#notation
CHEBI:8382

Additional References

Wikipedia:Prednisone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Prednisone
DRON_00010000
8640
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CHEBI:8382
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CHEBI:8382
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37962
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BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000060
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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http://purl.obolibrary.org/obo/DOID_0081312
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https://w3id.org/def/predibionto#has_drug_102919
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t307477
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