Discuss This Drug

Prednisone

CHEBI:CHEBI_8382

Definition

A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Chemical Information

Molecular Formula
C21H26O5
Molecular Mass
358.42810
Charge
0
SMILES
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
InChI
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChIKey
XOFYZVNMUHMLCC-ZPOLXVRWSA-N

Alternative Names

  • 1,2-Dehydrocortisone
  • 1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
  • 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
  • 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
  • Dehydrocortisone
  • prednison
  • prednisona
  • prednisone
  • prednisonum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Prednisone
DRON_00010000
8640
core#notation
CHEBI:8382

Additional References

Wikipedia:Prednisone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
TABLET, MULTILAYER, EXTENDED RELEASE
labeler_name
Skyepharma Production SAS
application_number
ANDA088703
product_ndc
68788-8663
spl_id
ee18acd6-7736-3e53-e053-2a95a90afa71
listing_expiration_date
20241231
marketing_start_date
20241104
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Prednisone
DRON_00010000
8640
oboInOwl#id
CHEBI:8382
generic_name
PREDNISONE MICRONIZED ANHYDROUS
brand_name
PredniSONE Tablets, USP, 20 mg
brand_name_base
PredniSONE Tablets, USP, 20 mg
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37962
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000060
package_ndc
71205-460-05
route
ORAL
package_description
5 kg in 1 DRUM (64958-0002-3)
package_marketing_start_date
20210623
nui
N0000175450
active_ingredient_strength
1 kg/kg
active_ingredient_name
PREDNISONE ACETATE
upc
0372789426051
spl_set_id
016d65c3-fff2-4e0c-9025-e2083cfa6a1f
rxcui
763185
manufacturer_name
RedPharm Drug Inc.
has_treatment
http://purl.obolibrary.org/obo/DOID_0081412
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_102919
owl#annotatedSource
t307477
owl#someValuesFrom
t3005483
core#notation
CHEBI:8382
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
unii
VB0R961HZT