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nintedanib

CHEBI:CHEBI_85164

Definition

A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer.

Chemical Information

Molecular Formula
C31H33N5O4
Molecular Mass
539.62480
Charge
0
SMILES
COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1
InChI
InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-
InChIKey
XZXHXSATPCNXJR-ZIADKAODSA-N

Alternative Names

  • BIBF 1120
  • BIBF-1120
  • BIBF1120
  • methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
  • nintedanib

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1592737
oboInOwl#hasDbXref
Wikipedia:Nintedanib
core#notation
CHEBI:85164

Additional References

Wikipedia:Nintedanib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1592737
oboInOwl#hasDbXref
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oboInOwl#id
CHEBI:85164
core#notation
CHEBI:85164
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_65207
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http://purl.obolibrary.org/obo/DOID_1580
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https://w3id.org/def/predibionto#has_drug_112793
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https://w3id.org/def/predibionto#has_side_effect37090
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t2914940