edoxaban

CHEBI:CHEBI_85973

Definition

A monocarboxylic acid amide that is used (as its tosylate monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism.

Chemical Information

Molecular Formula: C24H30ClN7O4S
Molecular Mass: 548.05800
Charge: 0
SMILES: CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1
InChI: InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1
InChIKey: HGVDHZBSSITLCT-JLJPHGGASA-N

Alternative Names

DU-176
edoxaban
N(1)-(5-chloropyridin-2-yl)-N(2)-{(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl}ethanediamide

Treatment Applications

lateral sinus thrombosis
DOID:3574

View Disease →
obsolete pulmonary vascular disorder
DOID:5455

View Disease →
pulmonary embolism and infarction
DOID:8516

View Disease →

Drug Classification

monocarboxylic acid amide
CHEBI:29347

View Class →
tertiary amino compound
CHEBI:50996

View Class →
chloropyridine
CHEBI:39173

View Class →
thiazolopyridine
CHEBI:46956

View Class →
t309992
t310039
t310438
t310804

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref: Wikipedia:Edoxaban
DRON_00010000: 1599538
core#notation: CHEBI:85973

Additional References

Wikipedia:Edoxaban

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Wikipedia:Edoxaban
DRON_00010000: 1599538
oboInOwl#id: CHEBI:85973
core#notation: CHEBI:85973
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_68581
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of: http://purl.obolibrary.org/obo/CHEBI_85976
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
rdf-schema#range: https://w3id.org/def/predibionto#has_drug_113241
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect37188
chebi#is_conjugate_acid_of: http://purl.obolibrary.org/obo/CHEBI_85976
owl#annotatedSource: t310978
owl#someValuesFrom: t3003836