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Pyrimethamine

CHEBI:CHEBI_8673

Definition

An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

Chemical Information

Molecular Formula
C12H13ClN4
Molecular Mass
248.71100
Charge
0
SMILES
CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
InChI
InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
InChIKey
WKSAUQYGYAYLPV-UHFFFAOYSA-N

Alternative Names

  • 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
  • 2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
  • 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
  • 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
  • 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
  • 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
  • 5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
  • CD
  • Chloridine
  • Chloridyn
  • Diaminopyritamin
  • Ethylpyrimidine
  • pirimetamina
  • Primethamine
  • pyrimethamine
  • pyrimethaminum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Pyrimethamine
DRON_00010000
9010
core#notation
CHEBI:8673

Additional References

Wikipedia:Pyrimethamine

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Additional Attributes

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9010
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CHEBI:8673
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RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38068
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