Discuss This Drug

Ramipril

CHEBI:CHEBI_8774

Definition

A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.

Chemical Information

Molecular Formula
C23H32N2O5
Molecular Mass
416.51060
Charge
0
SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O
InChI
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChIKey
HDACQVRGBOVJII-JBDAPHQKSA-N

Alternative Names

  • (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
  • (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
  • Altace (TN)
  • ramipril
  • Ramipril
  • Ramiprilum
  • Tritace

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:8774
DRON_00010000
35296
oboInOwl#hasDbXref
Wikipedia:Ramipril

Additional References

Wikipedia:Ramipril

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
spl_id
0f13188d-4f74-4370-b937-64c120cdd5dd
package_ndc
68382-144-01
marketing_start_date
20160830
package_description
500 TABLET in 1 BOTTLE (68382-374-05)
package_marketing_start_date
17-OCT-02
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE
labeler_name
Dr.Reddy's Laboratoriees Limited
application_number
ANDA076549
product_ndc
65841-656
rxcui
845489
manufacturer_name
REMEDYREPACK INC.
unii
L35JN3I7SJ
spl_set_id
5fb23b7d-ed2b-4984-89c8-d0a509b917e1
core#notation
CHEBI:8774
active_ingredient_strength
1.25 mg/1
pharm_class_epc
Angiotensin Converting Enzyme Inhibitor [EPC]
pharm_class
Angiotensin-converting Enzyme Inhibitors [MoA]
pharm_class_moa
Angiotensin-converting Enzyme Inhibitors [MoA]
active_ingredient_name
RAMIPRIL
nui
N0000000181
upc
0372789415901
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_2746
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37687
owl#annotatedSource
t314403
owl#someValuesFrom
t1008604
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
35296
oboInOwl#hasDbXref
Wikipedia:Ramipril
oboInOwl#id
CHEBI:8774
generic_name
Ramipril
brand_name
ALTACE
brand_name_base
ALTACE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77496
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723853