Discuss This Drug

sildenafil

CHEBI:CHEBI_9139

Definition

A pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position.

Chemical Information

Molecular Formula
C22H30N6O4S
Molecular Mass
474.57600
Charge
0
SMILES
CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
InChI
InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
InChIKey
BNRNXUUZRGQAQC-UHFFFAOYSA-N

Alternative Names

  • 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
  • 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
  • sildenafil

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9139
DRON_00010000
136411
oboInOwl#hasDbXref
Wikipedia:Sildenafil

Additional References

Wikipedia:Sildenafil

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
FOR SUSPENSION
application_number
ANDA214641
product_ndc
31722-136
package_description
1000 g in 1 CONTAINER (51552-1352-7)
route
INTRAVENOUS
package_ndc
71610-679-02
spl_id
0c892f95-15d6-52ab-e063-6394a90a1b33
labeler_name
AX Pharmaceutical Corp.
marketing_start_date
20070603
package_marketing_start_date
20201030
core#notation
CHEBI:9139
pharm_class_epc
Phosphodiesterase 5 Inhibitor [EPC]
pharm_class
Phosphodiesterase 5 Inhibitors [MoA]
pharm_class_moa
Phosphodiesterase 5 Inhibitors [MoA]
upc
0327241069109
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
active_ingredient_strength
10 mg/12.5mL
active_ingredient_name
SILDENAFIL
nui
N0000020026
spl_set_id
ef44442c-355e-7b8b-e053-2a95a90a2190
manufacturer_name
XLCARE Pharmaceuticals INC.
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
136411
oboInOwl#hasDbXref
Wikipedia:Sildenafil
oboInOwl#hasAlternativeId
CHEBI:600437
oboInOwl#id
CHEBI:9139
generic_name
Sildenafil citrate
brand_name
Sildenafil citrate
brand_name_base
Sildenafil citrate
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_71942
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
2637056
unii
3M7OB98Y7H
listing_expiration_date
20241231
has_treatment
http://purl.obolibrary.org/obo/DOID_4762
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38305
owl#annotatedSource
t317793
owl#someValuesFrom
t2909286