sildenafil
CHEBI:CHEBI_9139
Definition
A pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position.
Chemical Information
- Molecular Formula
- C22H30N6O4S
- Molecular Mass
- 474.57600
- Charge
- 0
- SMILES
- CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
- InChI
- InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
- InChIKey
- BNRNXUUZRGQAQC-UHFFFAOYSA-N
Alternative Names
- 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
- 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
- sildenafil
Drug Classification
-
piperazinesView Class →
CHEBI:26144
-
sulfonamideView Class →
CHEBI:35358
-
pyrazolopyrimidineView Class →
CHEBI:38669
-
t316688
-
t317059
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 136411
- oboInOwl#hasDbXref
- Wikipedia:Sildenafil
- core#notation
- CHEBI:9139
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- FOR SUSPENSION
- application_number
- ANDA214641
- product_ndc
- 31722-136
- package_ndc
- 51552-1352-7
- marketing_start_date
- 20070603
- labeler_name
- TruPharma LLC
- listing_expiration_date
- 20241231
- spl_id
- 0ac3e254-7b92-631e-e063-6294a90a4bf3
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 136411
- oboInOwl#hasDbXref
- Wikipedia:Sildenafil
- oboInOwl#hasAlternativeId
- CHEBI:600437
- oboInOwl#id
- CHEBI:9139
- generic_name
- Sildenafil citrate
- brand_name
- Sildenafil citrate
- brand_name_base
- Sildenafil citrate
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_71942
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- route
- INTRAVENOUS
- package_description
- 10 TABLET, FILM COATED in 1 BOTTLE (61919-755-10)
- manufacturer_name
- XLCARE Pharmaceuticals INC.
- package_marketing_start_date
- 20160815
- has_treatment
- http://purl.obolibrary.org/obo/DOID_4762
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect38305
- owl#annotatedSource
- t317793
- owl#someValuesFrom
- t2909286
- rxcui
- 2637056
- unii
- 3M7OB98Y7H
- spl_set_id
- f904d269-2708-d62f-e053-6394a90a8322
- upc
- 0382982063304
- active_ingredient_strength
- 10 mg/12.5mL
- active_ingredient_name
- SILDENAFIL
- nui
- N0000020026
- core#notation
- CHEBI:9139
- pharm_class_epc
- Phosphodiesterase 5 Inhibitor [EPC]
- pharm_class
- Phosphodiesterase 5 Inhibitors [MoA]
- pharm_class_moa
- Phosphodiesterase 5 Inhibitors [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class