Discuss This Drug

Spironolactone

CHEBI:CHEBI_9241

Definition

A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Chemical Information

Molecular Formula
C24H32O4S
Molecular Mass
416.57448
Charge
0
SMILES
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]33CCC(=O)O3)[C@]1([H])[C@@H](CC1=CC(=O)CC[C@]21C)SC(C)=O
InChI
InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
InChIKey
LXMSZDCAJNLERA-ZHYRCANASA-N

Alternative Names

  • 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
  • espironolactona
  • spironolactone
  • Spironolactone
  • spironolactonum
  • spironolattone

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
9997
oboInOwl#hasDbXref
Wikipedia:Spironolactone
core#notation
CHEBI:9241

Additional References

Wikipedia:Spironolactone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
9997
oboInOwl#hasDbXref
Wikipedia:Spironolactone
oboInOwl#hasAlternativeId
CHEBI:45692
oboInOwl#id
CHEBI:9241
core#notation
CHEBI:9241
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35703
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_682
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38383
owl#annotatedSource
t321247
owl#someValuesFrom
t929134