Tramadol

CHEBI:CHEBI_9648

Definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.

Chemical Information

Molecular Formula: C16H25NO2
Molecular Mass: 263.37520
Charge: 0

Alternative Names

(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
CG-315E
E-265
rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
tramadol
tramadolum
U-26225A

Drug Classification

racemate
CHEBI:60911

View Class →
t323485
t323535
t323603
t323616
t323726
t323752
t323812
t323981
t324053
t324060
t324250
t324325
t324462
t324512
t324573
t324586
t324592
t324635
t324667
t324682
t324784

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref: Reaxys:2943832
DRON_00010000: 10689
core#notation: CHEBI:9648

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

dosage_form: TABLET, COATED
product_ndc: 61281-8500
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_48878
BFO_0000051: http://purl.obolibrary.org/obo/CHEBI_75731
chebi#is_conjugate_base_of: http://purl.obolibrary.org/obo/CHEBI_75736
listing_expiration_date: 20241231
marketing_start_date: 20110122
spl_id: 1f94c73e-1add-bbd4-e063-6294a90a7a37
labeler_name: Virupaksha Organics Limited
oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Reaxys:2943832
DRON_00010000: 10689
oboInOwl#id: CHEBI:9648
generic_name: tramadol hcl
brand_name: TRAMADOL HCL ER
brand_name_base: ConZip
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053: http://purl.obolibrary.org/obo/DRON_00723856
package_description: 90 TABLET, COATED in 1 BOTTLE (76420-732-90)
package_ndc: 72162-2132-2
product_type: BULK INGREDIENT
marketing_category: BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number: ANDA091607
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect34371
chebi#is_conjugate_acid_of: http://purl.obolibrary.org/obo/CHEBI_75736
owl#someValuesFrom: t3847950
owl#annotatedSource: t324727
route: ORAL
package_marketing_start_date: 20020620
rxcui: 2692878
manufacturer_name: Palmetto Pharmaceuticals, Inc.
unii: 362O9ITL9D
spl_set_id: 0742ec44-f8b4-45c5-a36e-2638bdaa2e44
core#notation: CHEBI:9648
dea_schedule: CIV
pharm_class: Opioid Agonist [EPC]
brand_name_suffix: Extended-Release
upc: 0347335860832
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
has_treatment: http://purl.obolibrary.org/obo/DOID_573
active_ingredient_strength: 50 kg/50kg
active_ingredient_name: ACETAMINOPHEN