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Triamcinolone

CHEBI:CHEBI_9667

Definition

A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections.

Chemical Information

Molecular Formula
C21H27FO6
Molecular Mass
394.43390
Charge
0
SMILES
[H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
InChIKey
GFNANZIMVAIWHM-OBYCQNJPSA-N

Alternative Names

  • (11beta,16alpha)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 11beta,16alpha,17alpha,21-tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione
  • 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 9alpha-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 9alpha-fluoro-16alpha-hydroxyprednisolone
  • Fluoxyprednisolone
  • triamcinolona
  • triamcinolone
  • triamcinolonum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
10759
oboInOwl#hasDbXref
Wikipedia:Triamcinolone
core#notation
CHEBI:9667

Additional References

Wikipedia:Triamcinolone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10759
oboInOwl#hasDbXref
Wikipedia:Triamcinolone
oboInOwl#id
CHEBI:9667
generic_name
Triamcinolone acetonide crystallized sterile
brand_name
Triasil
brand_name_base
Triasil
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50857
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_8386
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000067
marketing_start_date
19581023
labeler_name
Pacira Pharmaceuticals, Inc.
product_ndc
51927-1326
route
INTRA-ARTERIAL
package_ndc
51927-1326-0
spl_id
ac924e68-87ab-4172-b702-fd705d452ddc
listing_expiration_date
20241231
rxcui
2665617
manufacturer_name
MidAmerica Pharmaceuticals
package_marketing_start_date
09-JUL-13
package_description
1 VIAL, SINGLE-DOSE in 1 CARTON (67457-621-02) / 1 mL in 1 VIAL, SINGLE-DOSE
application_number
ANDA213619
dosage_form
INJECTION, POWDER, FOR SUSPENSION, EXTENDED RELEASE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
unii
I7GT1U99Y9
spl_set_id
de5bad69-a014-4e25-b1b9-214373ca57a5
Name
http://purl.obolibrary.org/obo/DOID_0040068
has_treatment
http://purl.obolibrary.org/obo/DOID_9598
owl#annotatedSource
t324776
owl#someValuesFrom
t3349758
active_ingredient_strength
.1 mg/.1g
active_ingredient_name
TRIAMCINOLONE HEXACETONIDE
core#notation
CHEBI:9667
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
nui
N0000175450
upc
0382804071302
brand_name_suffix
2%
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class