Verapamil

CHEBI:CHEBI_9948

Definition

A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.

Chemical Information

Molecular Formula: C27H38N2O4
Molecular Mass: 454.60160
Charge: 0

Alternative Names

rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
verapamil
Verapamil
verapamilo
verapamilum

Drug Classification

racemate
CHEBI:60911

View Class →
t323466
t323534
t323774
t323855
t323935
t323987
t323988
t324093
t324128
t324208
t324351
t324619
t324632
t324680

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

core#notation: CHEBI:9948
oboInOwl#hasDbXref: Wikipedia:Verapamil
DRON_00010000: 11170

Additional References

Wikipedia:Verapamil

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route: INTRAVENOUS
package_ndc: 55289-723-90
spl_id: ff572f24-9420-4ac1-8ccf-e5db94e435d4
package_description: 54000 CAPSULE, EXTENDED RELEASE in 1 DRUM (60274-300-01)
product_ndc: 71872-7048
product_type: BULK INGREDIENT
marketing_category: BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form: CAPSULE, DELAYED RELEASE
labeler_name: EXELA PHARMA SCIENCES, LLC
application_number: ANDA075136
rxcui: 1665061
manufacturer_name: EXELA PHARMA SCIENCES, LLC
unii: V3888OEY5R
spl_set_id: 660a83a9-60be-42d5-bc70-fe384e93beaa
package_marketing_start_date: 20161017
listing_expiration_date: 20241231
marketing_start_date: 20060419
active_ingredient_strength: 480 kg/480kg
active_ingredient_name: VERAPAMIL HYDROCHLORIDE
upc: 0371205607302
core#notation: CHEBI:9948
pharm_class: Calcium Channel Blocker [EPC]
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect39469
owl#annotatedSource: t324781
owl#someValuesFrom: t3000662
oboInOwl#hasOBONamespace: chebi_ontology
oboInOwl#hasDbXref: Wikipedia:Verapamil
DRON_00010000: 11170
oboInOwl#id: CHEBI:9948
generic_name: verapamil Hydrochloride
brand_name: VERAPAMIL HCL
brand_name_base: VERAPAMIL HCL
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_77747
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053: http://purl.obolibrary.org/obo/DRON_00020325
BFO_0000051: http://purl.obolibrary.org/obo/CHEBI_77736
has_treatment: http://purl.obolibrary.org/obo/DOID_3892